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B7-H1 ANTIGEN
Descriptors Found:
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DeCS
Descriptor
English
:
Antigens, CD274
Descriptor
Spanish
:
Antígenos CD274
Descriptor
Portuguese
:
Antígenos CD274
Synonyms
English
:
B7-H1 Antigen
B7-H1 Immune Costimulatory Protein
B7H1 Immune Costimulatory Protein
CD274 Antigen
PD-L1 Costimulatory Protein
Programmed Cell Death 1 Ligand 1
Antigen, B7-H1
Antigen, CD274
B7 H1 Antigen
B7 H1 Immune Costimulatory Protein
CD274 Antigens
Costimulatory Protein, PD-L1
PD L1 Costimulatory Protein
Programmed Cell Death 1 Ligand 1 Protein
Tree Number:
D12.776.467.150.300
D12.776.543.095.300
D23.050.301.264.035.276.300
D23.050.301.285.400
D23.101.100.110.276.300
D23.529.168.300
Definition
English
:
An inhibitory B7
antigen
that has specificity for the T-CELL receptor PROGRAMMED
CELL DEATH
1 PROTEIN. CD274
antigen
provides negative signals that
control
and inhibit T-cell responses and is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR
IMMUNE EVASION.
See Related
English
:
Immunoglobulin Domains
History Note
English
:
2012
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
54623
Unique Identifier:
D060890
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS